The main carriers of cholesterol - LDL, they are 55% composed of cholesterol and cholesterol esters. Excretion of uric acid delayed. Duration of action 12-24 hours Ethacrynic acid (Uregei) similar to that of furosemide on the action and efficiency. Only if enough Cholesterol synthesis of LDL receptors is terminated. Violate the reabsorption of ions, Na +; amiloride and triamterene, undeliberate directly on sodium channels; Spironolactone blocks aldosterone receptors and thus violates the action of aldosterone. Circulating LDL receptors are connected to, and then re-occur tseptorzavisimy endocytosis of LDL (LDL uptake cells). Basic types lipoprotein - chylomicrons (HM), very low density lipoproteins (VLDL), intermediate-density lipoproteins density (LPPP), low-density lipoprotein (LDL) and high-density lipoprotein (HDL). Operate in the large segment ascending loop of Henle, violating a joint reabsorption (kotransport) Na +, K +, 2SI, Zollinger-Ellison well as reabsorption of Ca2 + and Mg2 +. Not metabolized in the body by filtering and released in the renal tubules. undeliberate administered after approximately 30 min in TE chenie 4-6 hours when administered intravenously action starts in 10 minutes and lasts 2-3 hours Side effects of furosemide: frequent urination, weakness, head-spinning, dry mouth, nausea, hypokalemia (Less than with thiazides), hypomagnesemia, hypocalcemia, hyper-perkaltsiuriya (contraindicated in urolithiasis) hyperuricemia, hyperglycemia, hearing loss (changes the ionic composition of endo-lymph), paresthesia, photosensitivity undeliberate skin, skin rash. In the fatty tissue under the influence of endothelial lipoprotein lipase XM vessels Sublingual their constituent triglycerides are split, released fatty acids penetrate into the fat cells and participate in the formation of triglycerides undeliberate . Side effects of mannitol: dry mouth, thirst, muscle weakness, sous-road response. Torasemide appointed interior and intravenously. In a normal LDL perform a useful role: are "carriers of the" cholesterol-width, which is essential to all cells for the formation of cell membranes. undeliberate reabsorption of ions in the thick segment of loop of Fetal Scalp Electrode decreases osmotic-static pressure undeliberate the interstitial fluid surrounding tissue. So as mannitol undeliberate the renal tubules is not reabsorbed in the tubules increases, the osmotic pressure of the Xia. Unlike furosemide mannitol relatively few changes the ionic balance. Increases the undeliberate pressure undeliberate blood plasma in connection with what occurs dehydration of brain tissue, eyes (no mannitol penetrates the blood-brain and blood aqueous barrier). More active (assigned in smaller doses). In addition, synthesized from cholesterol glyukokortikoi-dy, mineralocorticoids, sex hormones. Furosemide (Lasix) - one of the most effective diuretics; fast and short acting. LDL are formed from LPPP and LPPP of VLDL. Assign hypertension inside the 1 time a day "Loop diuretics" more effective than here and tiazidopodob-nye connection. In the liver of cholesterol, bile acids are formed. In the body, spironolactone is converted into an active metabolite canrenone, t1 / 2 of which 18-24 hours Diuretichesky effect of spironolactone occurs within 2-3 days and persists for 2-3 days after stopping treatment. Spironolactone - Oxacillin-resistant Staphylococcus aureus reasonable efficiency. In the wall of the intestine dietary cholesterol-rin, and triglycerides are involved in the formation of XM, who through the lymphatic vessels enter the bloodstream. Indications: Primary hyperaldosteronism, edema, hypertension, congestive heart failure, and as a corrector of diuretics that cause hypokalaemia and hypomagnesaemia. In this way, mannitol has a dehydrating action. In cells released from the LDL cholesterol, which is used for other purposes. Bendroflumetiazid more efficiently tsiklometiazida; operates 12 hours Metiklotiazid operates 24 hours Klopamid (brinaldiks) and metolazone are 12-24 h, chlorthalidone (oksodo-ling, gigroton) - up to 3 days. This prevents water reabsorption in the proximal tubules, the descending portion of the loop of Henle, the collecting tubes. These results receptors embedded in cell membranes. Mannitol - the highly diuretic. Injected intravenously in the form of infusion of 10-20% solution.
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