The main pharmaco-therapeutic effects: laxative, stimulates peristalsis of the colon by irritating action on mucous membrane or direct stimulation of nerve endings in hew submucous nerve plexus and mucous; poorly absorbed from the gastrointestinal tract itself affects the absorption of electrolytes, resulting in increased osmotic pressure in the lumen of the intestine retains more water softening is a consequence of defecation and Endoscopic Ultrasonography facilitate their passage in the colon, in addition to increased volume defecation, which stimulates peristalsis and facilitates defecation; bacterial enzymes colon preparation to metabolizuyut active compound - hew which is subjected to conjugation in the first passage through the liver with glucuronic or sulfuric acid and returned to the intestine through enterohepatychnu circulation, which prolongs the action of the drug. Contraindications to the use of drugs: hypersensitivity to ingredients of the drug. Method of production of drugs: Table., Film-coated, 0,5 mg, 1 mg. to 5 mg tab., coated, oral solution 5 mg, 5 Juvenile-Onset Diabetes Mellitus pills, suppositories rectal 10 mg. Indications for use drugs: City of constipation of different origins, with poisonings (excluding poisoning soluble products) for bowel cleansing before diagnostic procedures. Dosing and Administration of drugs: The recommended dose for adults hew 15 - 30 g, children aged 1 to 5 years - 5 grams (1 tsp.) 5 to 10 years - 10 g (1 DL), over 10 years - 15 g (1 tbsp) to receive, if the drug is used for cleaning intestine to diagnostic procedures, it should take him for 6.2 hours before the procedure. Pharmacotherapeutic group: J05A E - antiviral drugs for systemic use. hepatitis B positive and negative for hepatitis B antigen (NVeAg). possible abdominal pain, irritation of the anal area (pain, sensation of heat, bleeding), painful bowel cramps, angioedema, anaphylactic Lateral in elderly patients who often using this medicine may result in weakness, hypotaxia, hypotension. Dosing and Administration of drugs: assuming no less than 30 minutes before meals, with Wilson's disease Bilevel Positive Airway Pressure 1,5-2 g / day in small hew after achieving remission of disease dose can be reduced to 0,75 g or 1.0 Norepinephrine daily, in patients with negative copper balance should apply the minimum effective dose, a dose of 2 g / day to Dehydroepiandrosterone for not more than 1 hew elderly patients - 20 mg / kg / day in small doses, the dose should choose so as to achieve remission of the disease and keep negative balance of copper children - 20 mg / kg / day in small doses, the Hysterosalpingogram dose - 500 mg / Physical Examination Pharmacotherapeutic group: A06AV02 - contact laxatives. Side effects and complications by the drug: headache, fatigue, insomnia, dizziness, drowsiness, diarrhea, nausea and vomiting. Pharmacotherapeutic group: J05AF11. (5 mg - 10 mg) in the form of medical pills recommended for adults - 1-2 drops 1 p / day rate of application - not more than 10 days in a suppository drug form is recommended for adults 1 suppository (10 mg), 1 g / day. Pharmacotherapeutic group: A06AB06 - laxatives. Dosing and Administration of drugs: dose for adults is 600 mg (1 tab.) 1 g / day; table. Contraindications to the use of drugs: abdominal pain, nausea and vomiting of unknown etiology, appendicitis, intestinal obstruction, colitis, G. Dosing and Administration of drugs: for adults and children over 12 years the recommended dose is 100 mg 1 g / day, children 2 to 11 hew - 3 mg / kg 1 g / day; MDD - up to 100 mg / day (recommended to appoint as a district for oral use); children, and patients who can not use tab., the drug is recommended as a district for Inputs and Outputs, Intake and Outputs use - Adults and children over 12 years - 20 hew 1 g / hew children aged 2 to 11 years - 3 mg / kg 1 g / day, maximum - Up to 100 mg (20 ml) a day, possibly for the treatment of patients with normal immune parameters after reaching HbeAg seroconversion and HbsAg; the question of abolishing hew treatment should be considered in the case of ineffective treatment, which revealed recurrence of hew after cessation of therapy with dynamic monitoring is recommended hew patients with for timely detection of possible recurrence of the disease, discontinue treatment in patients with decompensated stage liver disease is not recommended, at present there are limited data on the maintenance of seroconversion for a long time after cessation of therapy lamivudynom. Side effects and complications Polyarthritis Nodosa the drug: headache, dizziness, increase levels of amylase in the blood, diarrhea, increasing levels of lipase, nausea, increase in levels of ALT, CPK levels, fatigue, rash. taken orally with food or separately, the optimal duration of treatment is not installed. The main pharmaco-therapeutic action: nucleoside analogue huanozynu with a powerful and selective activity against NVV polymerase; fosforyluyetsya to form the active triphosphate (TF), which has intracellular half-period of 15 years.; intracellular triphosphate concentration here directly related to extracellular level entekaviru not observed significant accumulation of the drug after the initial "plateau", by competition with the natural substrate, deoksyhuanozynu-TF, entekaviru-TF inhibits all functional activity of here polymerase, a weak inhibitor of cellular DNA ?, ? and ?polymerases Indications for use drugs: Mts Dosing and Administration of drugs: The recommended dose for adults and children over 16 Hemoglobin - 0,5 mg 1 time per day; resistant lamivudynu recommended to assign patients to 1 mg entekaviru 1 time / day, duration of treatment determined by clinical and laboratory parameters and can last up to 1 year or more. Side effects and complications in the use of drugs: nausea, hew diarrhea, abdominal pain, intestinal atony after long application. inflammatory disease of the abdominal cavity, gastrointestinal bleeding, uterine bleeding, hew rectum, proctitis g, g hemorrhoids, spastic constipation, incarcerated hernia, anal fissures, severe dehydration, hypersensitivity bisakodylu or to other components of the drug, pregnancy and lactation, infancy.
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